Key Highlights

• Comprehensive approach aimed at unraveling the complex mutational landscape of colorectal cancer, paving the way for targeted therapies and precision medicine.
• Utilizing the Sequence Read Archive (SRA) database from the National Center for Biotechnology Information (NCBI).
• Leveraging Picard tools for read group manipulation, duplicate marking, and generation of informative metrics
• Execution of GATK tools for filtering mutect calls, considering tumour segmentation, contamination, and artifact priors.
• Further work being done